Last updated: 2025-08-09
Checks: 2 0
Knit directory: mu-paper-dataviz/
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| File | Version | Author | Date | Message |
|---|---|---|---|---|
| Rmd | 7fb9e4f | sdhutchins | 2025-08-09 | Light tweaks. |
| Rmd | 3055051 | S. Hutchins | 2018-10-02 | workflowr::wflow_git_commit(all = TRUE) |
| html | 36b9ab2 | S. Hutchins | 2018-09-28 | Build site. |
| html | 5d39156 | S. Hutchins | 2018-09-28 | Added code and analysis for bar charts. |
| html | fbd5b51 | S. Hutchins | 2018-09-25 | Build site. |
| html | d4b0350 | S. Hutchins | 2018-09-25 | Build site. |
| html | 1921828 | S. Hutchins | 2018-09-25 | Build site. |
| html | 342ec6b | S. Hutchins | 2018-09-25 | Build site. |
| Rmd | 1720296 | S. Hutchins | 2018-09-25 | Start my new project |
| Rmd | 8e4901f | S. Hutchins | 2018-09-24 | Start workflowr project. |
Eric J. Vallender, PhD
Associate Professor, Department of Psychiatry and Human Behavior
University of Mississippi Medical Center
Faculty
Profile
Dr. Vallender’s research focuses on comparative genomics of neuropsychiatric disease, molecular evolution of the brain, and substance abuse functional genetics. His work includes characterizing the effects of genetic variation on ligand binding and intracellular signaling of the mu-opioid receptor.
This project involves data visualizations and analysis for research on mu opioid receptor biased agonism in rhesus macaques. The study was conducted by a collaborative team including:
Title: “In Vitro Effects of Ligand Bias on Primate
Mu Opioid Receptor Downstream Signaling”
Journal: International Journal of Molecular
Sciences
Volume: 21, Issue 11, Pages 3999
Date Published: June 3, 2020
DOI: 10.3390/ijms21113999
This project contains scripts and data visualizations for the OPRM1 manuscript focusing on characterizing MOR ligand bias in rhesus macaques. The research compares signaling bias patterns across different agonists and validates the translational utility of nonhuman primate models for opioid receptor studies.